Research Output

Publications & Scientific Basis

Defeating cancer with groundbreaking science and relentless discovery.

2025

2025 Preprint

MIND: Multimodal Integration with Neighbourhood-aware Distributions

Xing, H., & Yau, C.

bioRxiv, 2025.2009.2015.676314.

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2024

2024 Thesis

Deep molecular profiling of the anti-tumour immune response in immune checkpoint inhibitor-treated oesophageal cancer

Fuchs, H.

PhD thesis. University of Oxford.

2024 Conference abstract

Abstract CT208: High tumor monocyte content predicts long-term survival for patients with operable oesophageal cancer treated with neoadjuvant immunochemotherapy in the LUD2015-005 trial

Fuchs, H. S., James, S. A., Carroll, T. M., Xie, P. F., Chadwick, J. A., Parkes, D., Lord, S. R., Griffiths, L., Underwood, T., Karydis, I., Petty, R. T., Schuster-Böckler, B., Owen, R. P., Middleton, M. R., & Lu, X.

Cancer Research, 84(7_Supplement), CT208–CT208.

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2024 Conference abstract

Abstract PR017: A T-cell signature in circulating cell-free DNA at time of diagnosis predicts response to checkpoint inhibition

Xie, P., Etzioni, Z., Song, C.-X., Owen, R. P., Middleton, M. R., Lu, X., & Schuster-Boeckler, B.

Clinical Cancer Research, 30(21_Supplement), PR017–PR017.

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2023

2023 Journal article

Tumor monocyte content predicts immunochemotherapy outcomes in esophageal adenocarcinoma

Carroll, T. M., Chadwick, J. A., Owen, R. P., White, M. J., Kaplinsky, J., Peneva, I., Frangou, A., Xie, P. F., Chang, J., Roth, A., Amess, B., James, S. A., Rei, M., Fuchs, H. S., McCann, K. J., Omiyale, A. O., Jacobs, B. A., Lord, S. R., Norris-Bulpitt, S., … Team, L. U. D. P.

Cancer Cell, 41(7), 1222–1241 e1227.

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2023 Conference abstract

Long-term outcomes from adding durvalumab to neoadjuvant treatment of operable gastroesophageal cancers: Results from a multicenter study LUD2015-005

Middleton, M. R., Karydis, I., Lu, X., Ryan, A., Venhaus, R. R., Ramirez, K. A., Macri, M., Ricciardi, T., Lawrence, M., Scott-Brown, M., Griffiths, G. O., Collins, L., Griffiths, L., Wilding, S., Lord, S., Owen, R., & Petty, R. D.

Journal of Clinical Oncology, 41(4_suppl), 398–398.

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2023 Thesis

DNA methylation in late-stage oesophageal cancer

Xie, P.

PhD Thesis. University of Oxford.

2023 Conference abstract

Abstract LB131: Association between epigenetic heterogeneity of esophageal adenocarcinoma and response to first-line immunochemotherapy in LUD2015-005 Trial

Xie, P. F., Chang, J., Siejka-Zielińska, P., Inoue, M., Drożdż, M., Chadwick, J. A., Carroll, T. M., Owen, R. P., White, M. J., Kaplinsky, J., Amess, R., Middleton, M., Kriaucionis, S., Song, C., Schuster-Böckler, B., & Lu, X.

Cancer Research, 83(8_Supplement), LB131–LB131.

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2022

2022 Thesis

Antibodies, B cells, and immune tolerance in immunotherapy treated oesophageal cancer

Chadwick, J.

PhD Thesis. University of Oxford.

2022 Conference abstract

Abstract 1247: Comprehensive molecular profiling to predict first-line immunochemotherapy outcomes in inoperable esophageal adenocarcinoma

Carroll, T. M., Chadwick, J. A., Owen, R. P., White, M. J., Kaplinsky, J., Peneva, I., Frangou, A., Chang, J., Xie, P. F., Roth, A., Amess, B., Lou, H., McCann, K. J., Berridge, G., Fischer, R., Phetsouphanh, C., Omiyale, A. O., Jacobs, B.-A., Ahern, D., … Lu, X.

Cancer Research, 82(12_Supplement), 1247–1247.

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